||August: John Bosco was born at Becchi (Castelnuovo d'Asti) Italy.
||5th January: Dominic Pestarino, the confessor and spiritual director of Mary Dominica Mazzarello was born at Mornese (Alessandria) Italy.
||9th May: Mary Dominica Mazzarello, the co-foundress of the Institute of the Daughters of Mary Help of Christians was born in the Mazzarelli hamlet at Mornese, Italy.
||7th October: Don Bosco stopped at Mornese: first meeting with Mary Mazzarello.
||In May Don Bosco told his closest collaborators about his plan to found a women's religious congregation.
In June that same year the Holy Father, Pius IX, gave his approval.
During the summer Don Bosco entrusted Fr. Dominic Pestarino with the first draft of the Constitutions of the Daughters of Mary Help of Christians.
||5th August: Foundation of the Institute of the Daughters of Mary Help of Christians (FMA); first admissions to the novitiate and first professions in the presence of the founder, Don Bosco, and the Bishop of Acqui, Mgr, Joseph Sciandra. Mary Dominica Mazzarello was the first superior with the title of substitute or 'vicar'.;
prime vestizioni e professioni, presente il Fondatore don Giovanni Bosco e il Vescovo di Acqui mons. Giuseppe Sciandra.
Maria Domenica Mazzarello è la prima superiora con il titolo di “vicaria”
||The education authorities of Castelletto d'Orba officially recognised the first boarding school and the primary school of the FMA at Mornese.|
||8th October: the first FMA house was opened at Borgo San Martino (Alessandria) - Italy.
||28th August: Mary Dominica Mazzarello and the first FMA made their perpetual vows into the hands of Don Bosco.
||23rd January: diocesan approval of the Constitutions. 29th March: the first house in Turin-Valdocco was opened.
||1st September: the first house of the Institute outside Italy was opened at Nice (France).
9th November: Mother Mary Dominica Mazzarello and the first missionaries were received in audience by Pius IX.
14th November: the first six missionaries left for Uruguay.
||8th December: first printed edition of the Constitutions.
||4th February: the Mother house was transferred from Mornese to Nizza Monferrato (Italy).
||The Salesians and FMA began missionary work in Patagonia (Argentina).
12th April: the first boarding school was closed in Mornese, Italy.
|1881 ||February-March: Mother Mary Dominica Mazzarello was taken seriously ill a St. Cyr.
14th May Mother Mary Dominica Mazzarello died at Nizza Monferrato aged 44. She left 26 houses and 166 sisters.
On 18th August Sr. Catherine Daghero was elected superior general.
||From 11th - 22nd August the 1st General Chapter was held.
||Second edition of the Constitutions revised by Don Bosco.
||From 14th - 23rd August the 2nd General Chapter took place.
||31st January: the Founder Don Bosco died in Turin.
3rd December: the FMA established the first house in the southernmost tip of South America (Chile).
||Don Bosco's cause of canonization was introduced.
||8th October: the first foundation in the Middle East - Bethlehem.
||From 16th - 19th August the 3rd General Chaper took place.
||8th December: first foundation in Africa: Mers-el-Kebir (Algeria).
||The FMA returned to Mornese.
||From 4th - 7th September the 4th General Chapter was held.